Sleep problems in children with autism spectrum disorders, developmental delays, and typical development: a population-based study. J Sleep Res. 2008 Jun;17(2):197-206 Authors: Krakowiak P, Goodlin-Jones B, Hertz-Picciotto I, Croen LA, Hansen RL This study compared parent-reported sleep characteristics in 2- to 5-year-old children with autism spectrum disorders (ASD) to children with other developmental delays (DD) and typical development (TD). We included 529 children (303 ASD [167 males], 63 DD [46 males], and 163 TD [134 males]) enrolled in the CHARGE study, an ongoing population-based case-control study. The mean age of participants was 3.6 years (standard deviation, 0.8 years). ASD diagnosis was confirmed with Autism Diagnostic Interview-Revised (ADI-R) and Autism Diagnostic Observation Schedules (ADOS). Cognitive and adaptive functioning was assessed using Mullen Scales of Early Learning (MSEL) and Vineland Adaptive Behavior Scales (VABS), respectively. Demographic, medical and sleep history information were ascertained from California birth records, telephone interview, medical assessments at clinic visit, and parent-administered questionnaires. Fifty-three percent of children with ASD had at least one frequent sleep problem, followed by 46% of children with DD, and 32% of the TD group (P < 0.0001). Exploratory factor analyses of sleep history data yielded two factors: sleep onset problems and night waking. Children with ASD had marginally higher sleep onset factor scores and significantly higher night waking factor scores compared with the TD group. Factor scores for children with DD were intermediate between the ASD and TD groups. Cognitive or adaptive development did not predict severity of sleep problems in the ASD group. PMID: 18482108 [PubMed - in process] (Source: Journal of Sleep Research)]]>Low adiponectin associated with undiagnosed diabetes in cad patients Reduced levels of high-molecular-weight adiponectin are significantly associated with undiagnosed impaired glucose tolerance or Type 2 diabetes in patients with stable coronary artery disease (CAD), report investigators. (Source: MedWire News - Lipidology) Effects of altrenogest treatment of mares in late pregnancy on parturition and on neonatal viability of their foals Exp Clin Endocrinol DiabetesDOI: 10.1055/s-2008-1065367AbstractIn this study, effects of altrenogest treatment (0.088 mg/kg daily) given to mares during late gestation until parturition on the time and the process of foaling, neonatal adaptation and postnatal development were analysed. The number of animals was 6 in the treatment group and 7 in the control group. Gestational length tended to be shorter in mares given altrenogest. Birth weight of the foals and weight of the placenta did not differ between groups. The second stage of parturition was prolonged in the altrenogest-treated mares (p<0.05). Foals born to altrenogest-treated mares had a significantly lower respiratory rate than control foals during the first 30 minutes of life (p<0.05). At no time differences in heart rate and body temperature were found between groups. In foals of altrenogest treated mares, venous plasma pH was significantly higher than in control foals at 15 and 30 minutes after birth (p<0.05). Base excess in foals of altrenogest treated mares was significantly higher than in control foals at 45 minutes and up to 12 hours after birth (p<0.05). There were significantly more problems in the perinatal period (3/6) in foals born after altrenogest treatment to their dams than in control foals (0/7; p<0.05). In conclusion, treatment with altrenogest did not prevent parturition and its effectiveness to prevent abortion or preterm foalings in mares with disturbed pregnancies should be doubted. In addition, altrenogest treatment of mares affected adaptation of the foals to the extrauterine environment.[...]© Georg Thieme Verlag KG Stuttgart · New YorkGet connected:Table of contents | Abstract | Full text (Source: Experimental and Clinical Endocrinology and Diabetes) Prenatal stress in pigs: experimental approaches and field observations Exp Clin Endocrinol DiabetesDOI: 10.1055/s-2008-1065335AbstractPrenatal stress can affect the offspring's behaviour, physiology, and immune parameters. This paper summarises and discusses experimental and field studies on prenatal maternal stress in pigs. Often, elevated maternal corticosteroid concentrations during gestation are used to model prenatal stress. We used prolonged oral administration of cortisol (hydrocortisone acetate, HCA) to pregnant sows, which resulted in elevated maternal plasma and salivary cortisol concentrations. This treatment induced elevated fetal basal and adrenocorticotropic hormone (ACTH)-induced plasma cortisol concentrations, as demonstrated by a pilot study. Postnatally, it reduced birth weight of the piglets, and resulted in more live born piglets and higher preweaning mortality. In addition, it reduced the female offspring's salivary cortisol response to ACTH, and it enhanced the piglets’ novelty-induced locomotion and vocalisations, and the piglets were more aggressive in a social test. Some of these effects depended on the period of gestation during which maternal cortisol concentrations were elevated, and on the sex of the offspring. These results demonstrate that piglet physiology and behaviour can indeed be affected when the mother has elevated cortisol concentrations during gestation. Regular mixing of pregnant sows with unfamiliar sows during the last third of gestation did not affect maternal salivary cortisol concentrations. Also, it did not affect the piglets’ performance, behaviour, adrenocortical response to ACTH, or wound healing. Regular mixing of pregnant sows during the last third of gestation did not affect the piglets’ characteristics as studied in these experiments. However, performance and behaviour of piglets were highly influenced by the social rank of their mother during gestation. Our studies have demonstrated that piglets can be affected by elevated maternal cortisol concentrations during fetal development and by social rank of the pregnant sow during gestation.[...]© Georg Thieme Verlag KG Stuttgart · New YorkGet connected:Table of contents | Abstract | Full text (Source: Experimental and Clinical Endocrinology and Diabetes) Bob greene weighs in on emotional eating and weight loss in 'the best life diet' The fitness author recommends changing your lifestyle so that you exercise more and don't eat to comfort yourself. If he's good enough to be Oprah's personal trainer and food muse, surely he's got some tipsfor the rest of us. In his book "The Best Life Diet," exercise physiologist and fitness author Bob Greene expands on his signature concept: Weight loss is a lifetime commitment that starts within. (Source: L.A. Times - Health) Disulfiram: peripheral nerve disorders: 2 case reports. Page: 12 (Source: Reactions Weekly) Use of the oral contraceptive ethinylestradiol/drospirenone is not associated with an increase in body weight. Page: 12 (Source: Inpharma Weekly) Half-strength dosing of chloroquine and sulfadoxine in children with uncomplicated falciparum malaria leads to lower exposure and poor responses,. Page: 15 (Source: Inpharma Weekly) Rowing skill affects power loss on a modified rowing ergometer. Page: 1101DOI: 10.1249/MSS.0b013e3181668671Authors: HOFMIJSTER, MATHIJS J.; VAN SOEST, A. J.; DE KONING, JOS J. (Source: Medicine & Science in Sports & Exercise) Long-term outcomes after liver transplantation in children. Page: 247DOI: 10.1097/MOT.0b013e3282f94aabAuthors: Bucuvalas, John C a; Alonso, Estella b (Source: Current Opinion in Organ Transplantation) Getting "to the point": the experience of mothers getting assistance for their adult children who are violent and mentally ill. Page: 136DOI: 10.1097/01.NNR.0000319500.90240.d3Authors: Copeland, Darcy Ann; Heilemann, MarySue V. (Source: Nursing Research) Treatment of children with migraine in the emergency department: a qualitative systematic review. Page: 321DOI: 10.1097/PEC.0b013e31816ed047Authors: Bailey, Benoit MD, MSc, FRCPC +; McManus, Barbara Cummins MD, FRCPC * (Source: Pediatric Emergency Care) Management of glenoid bone loss in revision total shoulder arthroplasty. Page: 85DOI: 10.1097/BTE.0b013e3181728aafAuthors: Scalise, Jason J. MD (Source: Techniques in Shoulder & Elbow Surgery) Gao, congressional research service say bush administration improperly issued directive that limits states' abilities to expand schips The Bush administration improperly issued a policy directive last year that restricts states' abilities to expand their SCHIP programs, the Government Accountability Office and the Congressional Research Service said on Thursday during a House Energy and Commerce Health Subcommittee hearing, CQ Today reports. The Aug. 17, 2007, policy directive requires states to enroll 95% of children in families with incomes up to 200% of the federal poverty level before expanding coverage to children in families with incomes greater than 250% of the poverty level. During the hearing, Morton Rosenberg, a legal specialist for CRS, and Dayna Shah, managing associate general counsel for GAO, said the directive amounted to a regulation and should have been vetted in Congress using the same process as other administrative rules, according to CQ Today.The opinions from GAO and CRS "lend weight to Democrats' efforts to nullify the directive, something they have promised to do since it was issued," according to CQ Today. Subcommittee Chair Frank Pallone (D-N.J.) is sponsoring legislation (HR 5998) that would reverse the directive. He said, "The Aug. 17 directive would impose strict new requirements on states and beneficiaries that are not only impossible to achieve but make little, if any, sense." However, according to CQ Today, "Many Republicans support the principle behind the [directive], so Pallone's bill stands little chance of passing the Senate, where it could be filibustered." States have argued that meeting the enrollment requirement is impossible, and several states have filed lawsuits against the federal government to block the directive. The Bush administration says the directive is aimed at preventing families from dropping private health coverage to enroll in SCHIP.During the hearing, Rosenberg said a disproval resolution probably could still be passed by Congress to nullify the directive. Unlike stand-alone bills, disapproval resolutions cannot be filibustered in the Senate. Pallone said he would prefer to pass his bill because it also would require CMS to reconsider a request from New York state to expand its SCHIP, which the agency previously denied. According to a House Democratic aide, CMS officials were invited to testify at Thursday's hearing but said they would only do so if the hearing were held behind closed doors. CMS spokesperson Jeff Nelligan said he was unaware that the agency had been invited to testify (Wayne, CQ Today, 5/15). The GAO opinion is available online. (Source: kaisernetwork.org: Health Policy Daily Report) Transitions in progress (Source: Journal of Dentistry for Children) Oral characteristics of newborns (Source: Journal of Dentistry for Children) Traumatic dental injuries in the first year of life and associated factors in brazilian infants (Source: Journal of Dentistry for Children) Radiographic evaluation of pulpal and periapical response of dogs' teeth after pulpotomy and use of recombinant human bone morphogenetic protein-7 as a capping agent (Source: Journal of Dentistry for Children) Endodontics in primary molars using ultrasonic instrumentation (Source: Journal of Dentistry for Children) Influence of surface sealants on microleakage of composite resin restorations (Source: Journal of Dentistry for Children) Viability of streptococcus mutans toothbrush bristles (Source: Journal of Dentistry for Children) Clinical performance of class ii adhesive restorations in pulpectomized primary molars: 12-month results (Source: Journal of Dentistry for Children) Veneer retention of preveneered primary stainless steel crowns after crimping (Source: Journal of Dentistry for Children) Autosomal recessive robinow syndrome: a case report (Source: Journal of Dentistry for Children) Surgical removal of an oral pyogenic granuloma and subsequent root coverage with a pedicle graft (Source: Journal of Dentistry for Children) Management of supplemental permanent maxillary lateral incisors in association with talon cusp on the primary predecessors: a report of 3 cases (Source: Journal of Dentistry for Children) Langerhans cell histiocytosis: impact on the permanent dentition after an 8-year follow-up (Source: Journal of Dentistry for Children) Strategies for addressing restorative challenges in hiv-infected children (Source: Journal of Dentistry for Children) Oral rehabilitation of a child with amniotic band syndrome (Source: Journal of Dentistry for Children) Radicular cyst in a deciduous tooth: a case report and literature review (Source: Journal of Dentistry for Children) Orofacial aspects in noonan syndrome: 2 case report (Source: Journal of Dentistry for Children) A report of 2 cases of green pigmentation in the primary dentition associated with cholestasis caused by sepsis (Source: Journal of Dentistry for Children) Reconstruction and recovery of hemisectioned teeth using direct fiber-reinforced composite resin: case report (Source: Journal of Dentistry for Children) Intraoral findings of papillon-lefevre syndrome (Source: Journal of Dentistry for Children) Dentigerous cyst associated with an impacted anterior maxillary supernumerary tooth (Source: Journal of Dentistry for Children) Gastric bypass surgery restores sexual function in morbidly obese men Losing weight may help resolve erectile dysfunction in obese men. Morbid obesity can cause sexual dysfunction independent of other common confounders, including diabetes, hypertension and smoking. (Source: ScienceDaily Headlines) Pioneering induction of bone formation using embryonic stem cells Researchers have successfully creating bone tissue "in vivo", using embryonic stem cells. They imitated bone formation in embryos and children, which uses cartilage as a template. This new approach appears to be a promising way of repairing bone defects. Previous attempts to create bone using embryonic stem cells were unsuccessful. In the lab, there was clear evidence that these stem cells were differentiating into the bone lineage "in vitro", however this process stalled after implantation and no bone tissue was formed. Yet, this approach did lead to bone formation when cultured adult stem cells from bone marrow were used. This direct approach is, amongst others, involved in the formation of the bone found in the skull. (Source: ScienceDaily Headlines) Antibiotics over prescribed Doctors in Bahrain are endangering the health of children and adults by over prescribing antibiotics when treating patients, according to a Ministry of Health study. It found that a quarter of all medication prescribed in the country are antibiotics. Patients are pressuring doctors to give them antibiotics, prompting the Ministry to launch as awareness campaign and encourage doctors to prescribe less when treating people. (Source: Healthcare) Differential functional effects of novel mutations of the transcription factor foxl2 in bpes patients Mutations of the transcription factor FOXL2, involved in cranio-facial and ovarian development lead to the Blepharophimosis-Ptosis-Epicanthus Inversus Syndrome (BPES) in human. Here, we describe nine mutations in the open reading frame of FOXL2. Six of them are novel: c.292T>A (p.Trp98Arg), c.323T>C (p.Leu108Pro), c.650C>G (p.Ser217Cys) and three frameshifts. We have performed localization and functional studies for three of them. We have observed a strong cytoplasmic mislocalization induced by the missense mutation p.Leu108Pro located in the forkhead (FKH) domain of FOXL2. In line with this, transcriptional activity assays confirmed the loss-of-function induced by this variant. Interestingly, the novel mutation p.Ser217Cys, mapping between the FKH and the polyalanine domain of FOXL2 and producing a mild eyelid phenotype, led to normal localization and transactivation. We have also modeled the structure of the FKH domain to explore the potential structural impact of the mutations reported here and other previously reported ones. This analysis shows that mutants can be sorted into two classes: those that potentially alter protein-protein interactions and those that might disrupt the interactions with DNA. Our findings reveal new insights into the molecular effects of FOXL2 mutations, especially those affecting the FKH binding domain. © 2008 Wiley-Liss, Inc. (Source: Human Mutation) A note on tree gatekeeping procedures in clinical trials Dmitrienko et al. (Statist. Med. 2007; 26:2465-2478) proposed a tree gatekeeping procedure for testing logically related hypotheses in hierarchically ordered families, which uses weighted Bonferroni tests for all intersection hypotheses in a closure method by Marcus et al. (Biometrika 1976; 63:655-660). An algorithm was given to assign weights to the hypotheses for every intersection. The purpose of this note is to show that any weight assignment algorithm that satisfies a set of sufficient conditions can be used in this procedure to guarantee gatekeeping and independence properties. The algorithm used in Dmitrienko et al. (Statist. Med. 2007; 26:2465-2478) may fail to meet one of the conditions, namely monotonicity of weights, which may cause it to violate the gatekeeping property. An example is given to illustrate this phenomenon. A modification of the algorithm is shown to rectify this problem. Copyright © 2008 John Wiley & Sons, Ltd. (Source: Statistics in Medicine) Screening for copy-number alterations and loss of heterozygosity in chronic lymphocytic leukemia - a comparative study of four differently designed, high resolution microarray platforms Screening for gene copy-number alterations (CNAs) has improved by applying genome-wide microarrays, where SNP arrays also allow analysis of loss of heterozygozity (LOH). We here analyzed 10 chronic lymphocytic leukemia (CLL) samples using four different high-resolution platforms: BAC arrays (32K), oligonucleotide arrays (185K, Agilent), and two SNP arrays (250K, Affymetrix and 317K, Illumina). Cross-platform comparison revealed 29 concordantly detected CNAs, including known recurrent alterations, which confirmed that all platforms are powerful tools when screening for large aberrations. However, detection of 32 additional regions present in 2-3 platforms illustrated a discrepancy in detection of small CNAs, which often involved reported copy-number variations. LOH analysis using dChip revealed concordance of mainly large regions, but showed numerous, small nonoverlapping regions and LOH escaping detection. Evaluation of baseline variation and copy-number ratio response showed the best performance for the Agilent platform and confirmed the robustness of BAC arrays. Accordingly, these platforms demonstrated a higher degree of platform-specific CNAs. The SNP arrays displayed higher technical variation, although this was compensated by high density of elements. Affymetrix detected a higher degree of CNAs compared to Illumina, while the latter showed a lower noise level and higher detection rate in the LOH analysis. Large-scale studies of genomic aberrations are now feasible, but new tools for LOH analysis are requested. © 2008 Wiley-Liss, Inc. (Source: Genes, Chromosomes and Cancer) The prevalence and clinical impact of pulmonary artery sling on school-aged children: a large-scale screening study Airway obstruction is a leading cause of mortality and morbidity in patients with pulmonary artery sling (PAS). Early identification of PAS is imperative for prompt initiation of appropriate treatments.Our aim was to investigate the prevalence and clinical impact of PAS on school-aged children through a large-scale pre-sports participation cardiovascular screening (PPCVS) study.A total of 186,213 school-aged children underwent portable two-dimensional echocardiography (2DE) study in a PPCVS study between 2001 and 2004 in Taichung City, Taiwan. We prospectively collected data on the prevalence of PSA, demographics, clinical features, tracheo-bronchial anomalies (TBA), on computed tomography (CT), pulmonary function test (PFT), follow-up data in 1 year, and clinical outcomes.PAS was identified in 11 children (8 males/3 females) with a median age of 13 years (range: 7.2-13.7 years). The prevalence of PAS was 1 in 17,000 school-aged children. The majority of children with PAS had recurrent broncho-pulmonary infections (90.9%) and asthmatic cough (81.8%), which had a low positive predictive value of PAS ( (Source: Pediatric Pulmonology) Combination of gemcitabine and docetaxel in the treatment of children and young adults with refractory bone sarcoma The combination of gemcitabine and docetaxel has demonstrated promise in sarcomas diagnosed in adults. In the current study, the toxicity and efficacy of this combination were evaluated in pediatric sarcomas.A retrospective case review of 22 patients with recurrent or refractory bone or soft-tissue sarcomas who received gemcitabine (at a dose of 675 mg/m2 intravenously on Days 1 and 8) and docetaxel (at a dose of 75-100 mg/m2 intravenously on Day 8) was undertaken.The patients (ages 8-23 years) received a total of 109 courses of chemotherapy (median, 4 courses; range, 1-13 courses). Seventeen patients had osteosarcoma, 2 patients had Ewing sarcoma family of tumors (ESFT), 1 patient had a malignant fibrous histiocytoma (MFH), 1 patient had a chondrosarcoma, and 1 patient had an undifferentiated sarcoma. Of the 14 patients evaluable for response, the patient with an MFH achieved a complete response (CR), 3 patients with osteosarcoma achieved a partial response (PR), and 2 patients (1 with ESFT and 1 with osteosarcoma) had stable disease (SD). The overall objective response (CR + PR) rate was 29%. Median duration of response (CR + PR + SD) was 4.8 months (range, 1.6-13 months). The toxicity was manageable and consisted primarily of thrombocytopenia and neutropenia.In the current study, gemcitabine in combination with docetaxel was found to be well tolerated and demonstrated antitumor activity in children and adolescents with recurrent or refractory osteosarcoma and MFH. Further evaluation of this drug combination is warranted in these patients. Cancer 2008. © 2008 American Cancer Society. (Source: Cancer) [meniscal allograft transplantation.] Related Articles | | |||||||||||||||||||||||||||
[Meniscal allograft transplantation.]
Orthopade. 2008 May 17;
Authors: Lewinski G
Loss of meniscal cartilage leads to degenerative arthritis. Therefore, it is important to save the meniscus whenever possible. But not all damaged menisci can be treated by partial resection or repair. The concept of meniscal transplantation has been suggested and has been become more common in recent years. Meniscal transplantation should be considered for the young patient who has not developed advanced osteoarthritis. Ligament stability and normal knee alignment are further requirements for meniscal transplantation. At this time, meniscal allografts provide the best a priori conditions to prevent degenerative arthritis, but the use of allografts includes the risk of disease transmission. Open and arthroscopically assisted techniques have been described. Correct size matching and positioning as well as secure fixation of the meniscal horn are important for successful meniscal allograft transplantation. Even though controlled clinical studies have not yet provided clear evidence that meniscal transplantation prevents degenerative arthritis, pain relief and functional improvement have been found in follow-up studies.
PMID: 18483803 [PubMed - as supplied by publisher]
(Source: Der Orthopade)]]>Awesome.
But let me tell you something before others get to you...
Two things: You don't need to jump on any current diet craze and you don't need to start exercising for hours each day.
Just ask your physician. Any physician worth her salt will tell you that it's not about dieting, it's about reshaping your lifestyle.
If you want to start losing weight, just slightly tweak the habits you are already used to.
Eat, but eat different. Don't sit when you can stand. They are little things, but...
...it's the little things that make up the extra inches around your waist line!
Easy And Fast Weight Loss
We strive to provide only quality articles, so if there is a specific topic related to diets that you would like us to cover, please contact us at any time.
And again, thank you to those contributing daily to our Lose Weight Fast and Easy website.
Turning 50 prompts 75-pound weight loss
Barbara Aldrich can hardly remember a time when she wasn't a little overweight.
Star Jones blasts Walters for contents of memoir
Nearly two years after Star Jones left "The View" on rocky terms, the 46-year-old TV personality has criticized former boss Barbara Walters for writing about her.
Student educates himself, loses 180 pounds
Gathering together for old-fashioned, home-cooked meals was just a way of life for Brandon Hollas, who was raised on his family's farm in Cameron, Texas.
Fat to fitness instructor: Boot camp helps man lose 120 pounds
Two years ago, Tim Lenczowski dreaded walking from the parking lot into his office.
Teacher loses 120 pounds, drops seven dress sizes
Hardly a day that goes by that you won't find Tracey Wygal working out at the gym.
Writer drops 168 pounds, blogs to inspire others
She was never really skinny or terribly overweight.
Larry the Cable Guy on Weight Loss: 'I'm Down an Olsen'
Comedian Larry the Cable Guy, who shed 50 lbs. since last year, jokes he's lost so much weight "I'm down an Olsen!"
Kirstie Alley Launching Her Own 'Weight-Loss Brand'
Kirstie Alley may have parted ways with Jenny Craig after a three-year relationship, but the actress is not leaving the weight-loss field, she tells PEOPLE exclusively.
Can Sugar Substitutes Make You Fat?
Diet-friendly sugar substitutes may not be so slimming after all. A new study in lab animals furthers the theory that zero-cal sweeteners throw your body out of whack and plump you up
Writer drops 168 pounds, blogs to inspire others
She was never really skinny or terribly overweight for most of her life.
Writer shares journey to her 168-pound weight loss
I'm often asked how I got started on my weight loss journey. I wish I had a simple, perky answer, but the truth is, I had a lot of internal housecleaning to do first.
Bad foods that are actually great for your waist
If you've been avoiding burgers, ice cream, and pizza thinking you're doing your waistline a favor, don't. They can actually help you lose weight -- and keep it off, too. Here are the hidden slim-down perks of five foods that get a bad rap and the best way to add each one back into your diet.
Sneaky little slim-down tricks
Health magazine went to the top weight-control experts for their No. 1 tips to get the weight off now. Take a look.
Obesity Drugs Work -- Modestly
Drugs won't lead to dramatic weight loss, a study finds, but they do take off pounds and have other health benefits
Strategies to curb your hunger while you lose
It's 9 p.m. and you know just where that bag of peanut M&Ms is -- it's stashed in the pantry behind the ultravirtuous oatmeal and seriously fortified cereal. Out of sight, but not out of mind.
5 foods that should have a place in your diet
Bad reputations tend to stick, even with foods. Continued negative press about a fruit, vegetable, or beverage is enough reason for many of us to banish it. Or maybe we indulge on occasion, but with a measure of guilt.
Watch Television, Lose Weight?
For some people, the first step to getting fit may be sitting on the couch and channel surfing
The heavy road to a weight-loss drug
The market potential for a weight-loss wonder drug is enough to make any Big Pharma CEO salivate. Trouble is, safe and effective fat-fighting treatments are a Holy Grail that continues to elude pharmacological researchers.
Gastric Bypass Lowers Risk of Death
Two new studies show that the surgery, while not for everyone, reduces the risks of diabetes and other obesity-related diseases
Can a 60-year-old drug cure obesity?
With more than 300 million obese people in the world, it's no surprise that prescription weight-loss drugs alone are a $600 million market -- or that those drugs rarely work well. Some, like Xenical and Meridia, also have significant side effects, such as raised blood pressure.
Do Diet Foods Lead to Weight Gain?
New research suggests that consuming low-calorie food and drink may actually increase your tendency to overeat
Snack strategies: 4 cases where eating between meals can work
When you snack, you can fill in nutritional gaps, boost your intake of fruits and vegetables, keep your mood on an even keel, and help with appetite and weight control.
Star Jones: I Had Gastric Bypass Surgery
Star Jones Reynolds has been candid about many issues in her life - getting fired from The View or rumors that her marriage was failing - but she's remained mum about the secret behind her weight loss.
Obesity Is Contagious, Study Finds
Research shows that who you're friends with can have a profound impact on whether you're overweight
Weight loss success: Andy Sorrells
Depressed and tired of trying diet after diet, Andy Sorrells began a faith-based weight loss program.
Weight loss success: Maggie Sorrells
No longer able to fit into a booth at a restaurant and too embarrassed to ask for seatbelt extensions on an airplane, Maggie Sorrells was desperate to lose weight.
Weight loss is all in your head
In the battle against fat, the heroes achieve what most of us only long for -- lasting weight loss. They're so unusual, they've become the subjects of ongoing research by scientists trying to finger just what it is that makes them stand out from the rest of dieting humanity.
Woman drops 110 pounds, 8 dress sizes
Three years ago Sharon Twitchell was miserable.
Weight loss success: Sharon Twitchell
Tired of squeezing into a size 22 and with her marriage on the verge of collapse, Sharon Twitchell decided it was time to change her life.
Studies Bring New Hope for Obese
New research shows that bariatric surgeries, like gastric bypass, are safer and more effective than originally thought, especially for teenagers and seniors. But patients have to be sure to watch their alcohol intake
Taking steps to lose weight at work
Could work actually make you fitter? You might think it unlikely as you sit in your office slumped in front of your computer, but a new desk designed at the Mayo Clinic could give you a proper work out.
ADHD drug use for youth obesity raises ethical questions
When Alex Veith was 11 years old, he was in a bad spot.
Neurological condition linked to obesity surgery
Some obese people who have weight-loss surgery, particularly younger women, develop a neurological condition most often seen in severe alcoholics and linked to a vitamin deficiency, researchers said Monday.
Get the diet scoop: 6 promising supplements, 6 to avoid
The sales pitches are irresistible: "Lose 2 Pounds a Day!" "Burn Fat Round the Clock!" "Learn the Amazing Weight-Loss Secret of Hollywood's Sex Symbols!" OK, maybe that's pushing it. But if diet pills could give you Eva Longoria's body, would you bother with the salads and stair-climbing?
TrimSpa in trouble after Smith's death
The death of sassy spokeswoman Anna Nicole Smith coupled with growing doubts about TrimSpa's controversial weight-loss products may prove too much for the closely held company, marketing experts said Thursday.
Dieters have Alli in weight-loss war
The FDA's decision to grant over-the-counter status to GlaxoSmithKline's weight loss drug Alli could have big implications on national health, but the drug is not a miracle cure, experts said.
Dr. Gupta: Things to know before taking alli
A fat-blocking weight-loss pill called alli is the first diet drug to be approved by the FDA for over-the-counter sales. It's a reduced-strength version of the prescription medication Xenical. Here's what I think you should keep in mind before considering this drug:
From 500 pounds to a new and rewarding life
On October 2, 2005, I weighed 500 pounds.
McKenna did many things right, dietitian says
Matt McKenna's dramatic weight loss gets high praise from one diet pro.
Fighting the fitness battle as you age
Turning 40 is a milestone in most people's lives. Among the rewards: Your kids are more independent; your career is more stable and you have more free time to pursue the things you love to do.
FTC settles with companies over unproved weight-loss claims
The marketers of four weight-control pills have agreed to pay a total of at least $25 million to settle allegations of deceptive advertising, the Federal Trade Commission announced Thursday
Diet pill marketers hit with false ad fines
The Federal Trade Commission said Thursday it fined marketers of such popular over-the-counter diet drugs as Xenadrine EFX and TrimSpa millions of dollars for using false advertising practices.
70 percent of dieters go solo, with no doctor, survey finds
Besides extra pounds, dieters also seem to carry a hefty independent streak. A survey finds that 70 percent of Americans who are trying to lose weight are following their own diet plans and have no interest in seeking a doctor's help.
A little biotech's big, risky bet on weight loss
The biotech Amylin is testing what could be the next blockbuster in the $40 billion market for weight loss products, or the treatment could just be a big fat flop.
Watch your weight, cut your cancer risk
The American Cancer Society said Thursday that keeping weight under control is the most important thing non-smokers can do to prevent the disease.
Lose weight without exercise
A California biotech could be on its way to a diet drug blockbuster or tiptoeing through a minefield depending on the performance of its next miracle weight loss treatment.
Here comes the microdiet
Forget fat and carbs - the key to weight loss could lie in micronutrients like amino acids, according to groundbreaking new research that will be of interest to food and pharmaceutical companies alike.
Your e-mails: Tips in battle of the bulge
CNN.com asked users to share their success stories in their fight against fat as well as thoughts and tips to getting fit. Here is a sampling from the responses, some of which have been edited:
Low fat, mo' fat: A faceoff
The recently released, groundbreaking eight-year federal study refuting the weight loss and disease fighting benefits of low-fat diets sparked controversy and has added to Americans' increasing confusion over what to eat. If you're thinking of ditching that low-fat diet, here's a quick comparison of the low-fat and high-fat (or mo'-fat) lifestyles.
NutriSystem lures men with pizza, sex
Nate Griffin, a former Army sergeant, watches what he eats. He's even tried juice diets to shed pounds. But ask him if he'd join a group to talk about weight loss and he cringes.
Common sense approach to eating
Steven Hawks, a professor of health science at Brigham Young University here, says phooey to dieting.
Biotech stock surges on diet drug study
Arena Pharmaceuticals stock surged as much as 23 percent Wednesday after the California biotech announced study results for its experimental weight loss drug.
Sanofi hoping for new wonder drug
An experimental drug from Sanofi-Aventis has been shown to have multiple benefits in treating heart disease and diabetes, the big French drugmaker announced Wednesday.
Diet stocks for the post-Atkins age
The bankruptcy filing of Atkins Nutritionals in late July signaled the twilight of America's latest diet obsession, as carb counters realized, to their amazement, that man cannot live on pork rinds...
This week in the medical journals
No comfort for colds
This week in the medical journals
Too much food, too little exercise
Weight Watchers gets nod from mag
Weight Watchers is the best overall diet plan, according to new Consumer Reports research.
Slow and steady wins weight-loss race
For many who overindulged in December, January is time to take steps to shed extra pounds put on from cookies and cocktails galore.
New diet squeezes in on weight-loss scene
A new eating-by-numbers method has arrived on the diet scene, and it's not Weight Watchers.
Kraft to team with South Beach Diet
Kraft Foods is about to get the seal of approval from the South Beach diet on some of its products, including Kraft cheese, Philadelphia Cream Cheese, Cool Whip and Planters peanuts, according to a published report.
"I've got a problem..."
Anyone who's seen Bill Clinton in the past few months ? speaking at the White House ceremony when his portrait was unveiled in May, delivering a ringing speech in support of John Kerry at the Democratic National Convention in July, signing copies of his book all over the world this summer ? couldn't help noticing that he was full of energy and looking mighty svelte.
What's behind the curb-your-carbs craze?
The latest diet dictionary spells evil "C-A-R-B."
Gorran: Atkins suit a 'quest for knowledge'
Businessman Jody Gorran says the Atkins diet is, in reality, unfriendly and almost cost him his life and he is filing suit against the promoters of the Atkins Diet and the estate of founder Dr. Robert Atkins. He spoke to CNN's Anderson Cooper about the case.
Chasing The Youth Pill Drugs that might extend human life are one of the hottest topics in biotech. Some of them are already her
The power of wishful thinking guarantees that just about anything can be successfully marketed as an elixir of youth. Pee, for instance. A multitude of websites extol the ability of "urine therapy"...
Low-carb dieters are way off target
Americans who've pledged allegiance to low carb diets are in for a rude shock. According to a new report Monday, consumers aren't cutting down on carbs as much as they thought they were.
Low-carb bubble about to burst?
Foodmakers keep it coming: Low-carb Doritos, low-carb Entenmann's chocolate chip cookies, Heinz' 'One Carb' ketchup, a low-sugar Krispy Kreme Doughnut.
The Pill that Will Make You Thin Pharma companies large and small are in hot pursuit of the blockbuster of all blockbusters--a d
As hospital food goes, the menu was positively four-star: chicken curry and rice, fruit salad, chocolate drops, and candy bars. For the two dozen hungry test subjects gathered for a meal at London'...
Keep An Eye On Weight Watchers The Atkins craze has hurt, but UBS analyst Andrew McQuilling sees hefty earnings ahea
In the past, two-time FORTUNE All-Star Andrew McQuilling has given our readers well-timed tips on such out-of-favor gems as Procter & Gamble, Gillette, and Estee Lauder (the makeup giant's stock is...
Of carbs and fads
The low-carb thing is getting pretty silly.
Atkins World When did carbs replace fat as nutritional enemy No. 1? What does it mean for the pork-rind industry? Is Wonder Brea
The Lexus RX-300--license plate EGGMAN1--barrels west on Route 30 in Pennsylvania's York County. We're on the road to Wellsville, a farm community blanketed in December's first snowfall. At the whe...
Shortsighted Investigating the bear case with one of the best
Most of us invest with the idea of our stock picks going up, not down. Not short-sellers. They are the Cassandras of the stock market, spotting problems on the horizon and waiting for them to unfol...
The Battle Of The Diet Docs THE LATE DR. ROBERT ATKINS BUILT HIS CONTROVERSIAL DIET INTO A $100 MILLION
Americans keep getting fatter. in 2001 more than 44 million people were obese, a figure that was up 74% from ten years earlier and is ballooning faster than our collective waistline. While that fac...
Dieting for Dollars These are boom times for the weight-loss industry. Can the big food companies be far behind?
Americans have never been bigger--and neither has the diet industry.
The Quest For The Antifat Pill Nature programmed us to overeat. Fen-Phen helped that, until it backfired. Safer drugs may be com
If the number you see on the bathroom scale is even more depressing than your 401(k)'s bottom line, take heart. Dozens of slimming aids are in the pharmaceutical pipeline.
Uphill Battle Few companies have tried harder than Union Pacific to help employees slim down. Why isn't it working?
Union Pacific Railroad has long known that many of its 48,000 employees--mostly middle-aged men--are overweight. That can be a dangerous problem for people who ply the rails. So 16 years ago the Om...
Better Managing Through Chemistry An abridged guide--and comprehensive formulary--to health and survival in the workplace.
Your boss has stopped saying hello in the morning. One of your underlings now goes to the weekly meeting that you're no longer invited to. Everybody at the office is looking tanned, fit, and rel...
How To Make A Weight Loss A Tax Gain
The recent IRS decision to define obesity as a disease means that certain costs of losing weight may now be deductible. To take a write-off, you must have a doctor's diagnosis that you are obese or...
The Ticker
--HEALTHY EARNINGS. Just in time for New Year's resolution season, Weight Watchers made an initial public offering of stock on Nov. 15. Shares of the 40-year-old weight-loss company rose 25% on the...
Rage Against The Ronald
You know who Ronald Perelman is, right? The Wall Street wheeler-dealer billionaire who controls Revlon and a bunch of other companies. Makes the society pages with his divorces (expensive) and marr...
Waist Not, Want Not
"I can't believe it. I gained five pounds last year. But I'll take them off. Honest."
Fad Diets: All Protein, No Proof
Stress is a popular topic. So's prostate cancer. But the thing most of my patients want to talk about is diet. They've all got friends who've lost 20 pounds in two weeks on a steak and bacon-and-eg...
Diet Menu: Salad, Seafood, and...Pork Rinds?!?
The popularity of low-carbohydrate/high-protein diets has had an unexpected side effect: a surge in pork-rind sales. The salty snacks have about nine grams of protein per serving and no carbohydrat...
SHRINK YOUR WEIGHT WHILE KEEPING YOUR WALLET PLUMP
THIS MONTH: -- How one Virginia man spent $12,000 to lose 80 pounds -- High-tech pianos that are truly grand
NEW WEAPONS IN THE WAR ON FAT WE'RE SPENDING $33 BILLION A YEAR TO GET THIN--AND STILL GAINING WEIGHT. MAYBE IT'S TIME TO ROLL O
Americans are so aware of their weight that even brownies on the grocery shelves cry "fat free" to catch the attention of the righteous, and closets across the land are stocked with jogging shoes. ...
PRODUCTS TO WATCH
THE WORLD'S SMALLEST FAX Compact enough to be slated for inclusion in an upcoming edition of the Guinness Book of Records, Ricoh Corp.'s PF-1 facsimile machine measures 11 by 7 inches -- it fits on...
DIET CENTERS ARE REALLY IN FAT CITY Ballooning baby-boomers are getting serious about shedding those pounds. Enter the pros -- w
FOR BABY-BOOMERS, it's the moment of truth. Not only are they turning fortysomething, so are their waistlines. The upshot: Just as fast as they can get the money out of their too-tight, five-pocket...
THE HUNT IS ON FOR AN ANTIFAT PILL Scientists are testing a plateful of anti-obesity compounds with few if any side effects. The
THE VENDING MACHINE stood in the research ward, ready to dispense its goodies whenever someone had the urge for a snack. Half the food slots contained protein-rich fare: barbecued chicken wings, le...
| Low Carbohydrate Diets By juliehart Low-carbohydrate diets or low carb diets, are food diet programs for weight loss and dietary health that suggest a reduced carbohydrate intake, with the success of the Atkins diet, several other low Read more... |
| Obesity Increases The Prostate Cancer Death Risk Obese men suffering from prostate cancer are two-and-a-half times more likely to die from it compared to normal-weight men, according to a recent study from Fred Hutchinson Cancer Research Read more... |
| The Warrior Diet The Warrior diet allows people to eat in the evening as much as they wish, without any calorie restrictions, while during daytime it allows for only small amounts of food. The diet, which Read more... |
| Seven Things You Should Know About Low Carb Diet By Sinta Makah 1. Any weight loss or diet plan, including low-carb plans like the induction phase of the Atkins Diet will result in water loss during the first week or two. However, one of the real beauties of Read more... |
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